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IRAP is an abbreviation for Interleukin-1 Receptor Antagonist Protein therapy. These anti-inflamatory proteins block the harmful effects of Interluekin-1 which is an inflammatory substance that has been shown to worsen osteoarthritis by causing destruction of cartilage.

After blood is drawn from the horse, it is incubated for 24 hours to maximize the levels of IRAP and is then put in a centrifuge to separate the blood cells from the serum. Then the serum is injected into the affected area every two weeks in a series of 3-4 treatments. This treatment is safe and is a good alternative to traditional joint injections.

Indications for the use of Irap II would be horses with arthritis, as a replacement treatment for HA and Corticosteroids, and horses that are no longer benefiting from traditional therapies.